verteporfin

Generic Name: verteporfin (VER te PORE fin)

Brand Names: Visudyne

What is verteporfin?

Verteporfin works by enhancing the eye's sensitivity to light. Verteporfin affects abnormal blood vessels in the eye.

Verteporfin is used together with "photodynamic" laser light therapy to treat blood vessel disorders in the eye caused by macular degeneration and other eye diseases.

Verteporfin may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about verteporfin?

You should not receive this medication if you are allergic to verteporfin, or if you have porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system).

Before receiving verteporfin, tell your doctor if you have liver or gallbladder disease, or if you are receiving radiation treatment.

Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when the medicine is injected.

Verteporfin will make your eyes and your skin more sensitive to light. After receiving verteporfin, you must protect your eyes and skin from natural sunlight and bright indoor light for at least 5 days..

Wear dark sunglasses and keep all parts of your skin covered with clothing. Sunscreen will not be effective in protecting you from UV rays during the 5-day period after you have received verteporfin.

What should I discuss with my health care provider before I receive verteporfin?

You should not receive this medication if you are allergic to verteporfin, or if you have porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system).

If you have certain conditions, you may need a dose adjustment or special tests to safely receive this medication. Before receiving verteporfin, tell your doctor if you have:

• 
  

  liver disease;

  
  


• 
  

  gallbladder disease; or

  
  


• 
  

  if you are receiving radiation treatment.

  
  

FDA pregnancy category C. Verteporfin may be harmful to an unborn baby. Before you receive verteporfin, tell your doctor if you are pregnant. Verteporfin can pass into breast milk and may harm a nursing baby. Do not receive this medication without telling your doctor if you are breast-feeding a baby.

How is verteporfin given?

Verteporfin is given as an injection through a needle placed into a vein. You will receive this injection in a clinic or hospital setting. The medicine must be given slowly through an IV infusion, and can take at least 10 minutes to complete.

Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when the medicine is injected.

You will receive laser light treatment to your eye(s) within 15 minutes after the start of your verteporfin infusion.

After receiving verteporfin, you must protect your eyes from natural sunlight and bright indoor light for at least 5 days.. For best protection, wear dark sunglasses whenever you are outdoors or while indoors under bright lighting.

You should not stay in the dark while you are indoors, as this can actually cause the drug to stay active in your body longer. It is best to spend your time in ambient indoor light such as indirect sunlight through a window, or low-wattage incandescent lighting. Avoid areas where you will be exposed to halogen or fluorescent light.

What happens if I miss a dose?

Since verteporfin is given by a healthcare professional only in preparation for laser light treatment, you will not be on a dosing schedule.

What happens if I overdose?

Seek emergency medical attention if you think you have received too much of this medicine.

Overdose symptoms may include severely decreased vision.

What should I avoid after I receive verteporfin?

Verteporfin will make your eyes and your skin more sensitive to light. Natural sunlight and bright indoor light can expose you to harmful UV rays, which may cause severe sunburn or damage to your vision.

Avoid exposure to sunlight, tanning beds, bright halogen lights, or other bright lighting for at least 5 days after you are treated with verteporfin.

To avoid exposing your skin to sunlight, keep all parts of your skin covered with clothing. Sunscreen will not be effective in protecting you from UV rays during the 5-day period after you have received verteporfin.

Verteporfin can cause side effects that may impair your vision. Be careful if you drive or do anything that requires you to be able to see clearly.

Verteporfin side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; sweating; dizziness; swelling of your face, lips, tongue, or throat. Tell your caregivers at once if you have a serious side effect such as:

• 
  

  severe decrease in vision;

  
  


• 
  

  sudden and severe pain;

  
  


• 
  

  severe redness or other discoloration of your eyes;

  
  


• 
  

  eye pain or seeing halos around lights;

  
  


• 
  

  feeling like you might pass out;

  
  


• 
  

  chest pain; or

  
  


• 
  

  warmth or tingly feeling under your skin.

  
  

Less serious side effects may include:

• 
  

  slight changes in your vision, seeing flashes of light;

  
  


• 
  

  dry eyes;

  
  


• 
  

  redness, swelling, or itching of your eyelids;

  
  


• 
  

  seeing flashes of light;

  
  


• 
  

  headache;

  
  


• 
  

  weak or tired feeling;

  
  


• 
  

  mild itching or skin rash;

  
  


• 
  

  constipation, nausea;

  
  


• 
  

  joint pain, muscle weakness;

  
  


• 
  

  fever, chills, body aches, sore throat, flu symptoms; or

  
  


• 
  

  pain, swelling, bleeding, or itching where the medicine was injected.

  
  

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Verteporfin Dosing Information

Usual Adult Dose for Macular Degeneration:

Subfoveal choroidal neovascularization: 6 mg/m2 body surface area intravenously over 10 minutes, once. The drug is photoactivated by 83 seconds of laser light administration (689 nm) commencing 15 minutes after start of the infusion.

Bilateral lesions in patients who have never undergone verteporfin therapy: 6 mg/m2 body surface area intravenously over 10 minutes, once. The drug is photoactivated by 83 seconds of laser light administration (689 nm) commencing 15 minutes after start of the infusion. The most aggressive lesion should be treated first. If, after the first treatment, an acceptable safety profile is identified, treatment of the second eye can commence no sooner than one week following the first course.

Bilateral lesions in patients who have undergone previous verteporfin therapy: 6 mg/m2 body surface area intravenously over 10 minutes, once. The drug is photoactivated by 83 seconds of laser light administration (689 nm) commencing 15 minutes after start of the infusion. If the patient showed an acceptable safety profile following the first course of verteporfin therapy then both eyes may be treated concurrently after a single administration of verteporfin. The more aggressive lesion should be treated first 15 minutes after the start of the verteporfin infusion. The treatment of the second eye should be initiated immediately at the end of the light treatment of the first eye using the same light dose and intensity as for the first eye. The treatment of the second eye should start no later than 20 minutes after the start of the verteporfin infusion.

Patients may be retreated in 3 months, if necessary.

Usual Geriatric Dose for Macular Degeneration:

Subfoveal choroidal neovascularization: 6 mg/m2 body surface area intravenously over 10 minutes, once. The drug is photoactivated by 83 seconds of laser light administration (689 nm) commencing 15 minutes after start of the infusion.

Bilateral lesions in patients who have never undergone verteporfin therapy: 6 mg/m2 body surface area intravenously over 10 minutes, once. The drug is photoactivated by 83 seconds of laser light administration (689 nm) commencing 15 minutes after start of the infusion. The most aggressive lesion should be treated first. If, after the first treatment, an acceptable safety profile is identified, treatment of the second eye can commence no sooner than one week following the first course.

Bilateral lesions in patients who have undergone previous verteporfin therapy: 6 mg/m2 body surface area intravenously over 10 minutes, once. The drug is photoactivated by 83 seconds of laser light administration (689 nm) commencing 15 minutes after start of the infusion. If the patient showed an acceptable safety profile following the first course of verteporfin therapy then both eyes may be treated concurrently after a single administration of verteporfin. The more aggressive lesion should be treated first 15 minutes after the start of the verteporfin infusion. The treatment of the second eye should be initiated immediately at the end of the light treatment of the first eye using the same light dose and intensity as for the first eye. The treatment of the second eye should start no later than 20 minutes after the start of the verteporfin infusion.

A decreased treatment effect has been reported in elderly patients

Patients may be retreated in 3 months, if necessary.

What other drugs will affect verteporfin?

The following drugs can interact with verteporfin. Tell your doctor if you are using any of these:

• 
  

  dimethyl sulfoxide (Rimso-50);

  
  


• 
  

  griseofulvin (Fulvicin, Grisactin);

  
  


• 
  

  polymyxin B (Polytrim, AK-Poly-Bac, Ocumycin, Polysporin Ophthalmic, Polytracin Ophthalmic);

  
  


• 
  

  diabetes medications you take by mouth;

  
  


• 
  

  birth control pills;

  
  


• 
  

  a diuretic (water pill);

  
  


• 
  

  a sulfa drug (Bactrim, Gantanol, Septra, and others);

  
  


• 
  

  medication used to prevent blood clots, such as alteplase (Activase), anistreplase (Eminase), clopidogrel (Plavix), dipyridamole (Persantine), streptokinase (Kabikinase, Streptase), ticlopidine (Ticlid), and urokinase (Abbokinase);

  
  


• 
  

  medicine to treat mental illness, such as chlorpromazine (Thorazine), fluphenazine (Prolixin), mesoridazine (Serentil), perphenazine (Trilafon), prochlorperazine (Compazine), thioridazine (Mellaril), or trifluperazine (Stelazine);

  
  


• 
  

  an antibiotic such as ciprofloxacin (Cipro), ofloxacin (Floxin), norfloxacin (Noroxin), levofloxacin (Levaquin), lomefloxacin (Maxaquin), and others;

  
  


• 
  

  a tetracycline antibiotic such as demeclocycline (Declomycin), doxycycline (Adoxa, Doryx, Oracea, Vibramycin), minocycline (Dynacin, Minocin, Solodyn, Vectrin), or tetracycline (Brodspec, Panmycin, Sumycin, Tetracap); or

  
  


• 
  

  a calcium channel blocker such as amlodipine (Norvasc), diltiazem (Tiazac, Cartia, Cardizem), nifedipine (Procardia, Adalat), verapamil (Calan, Covera, Isoptin, Verelan), and others.

  
  

This list is not complete and there may be other drugs that can interact with verteporfin. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

More verteporfin resources

• Verteporfin Side Effects (in more detail)
• Verteporfin Dosage
• Verteporfin Use in Pregnancy & Breastfeeding
• Verteporfin Drug Interactions
• Verteporfin Support Group
• 0 Reviews for Verteporfin - Add your own review/rating

• verteporfin Intravenous, Injection Advanced Consumer (Micromedex) - Includes Dosage Information


• Verteporfin MedFacts Consumer Leaflet (Wolters Kluwer)


• Verteporfin Monograph (AHFS DI)


• Visudyne Prescribing Information (FDA)

Compare verteporfin with other medications

• Macular Degeneration

Where can I get more information?

• Your doctor or pharmacist can provide more information about verteporfin.

See also: verteporfin side effects (in more detail)

Vesanoid

Pronunciation: TREH-tih-NO-in
Generic Name: Tretinoin
Brand Name: Generic only. No brands available.

Tretinoin can cause severe, even fatal, side effects. Therefore, it must be used only under close medical supervision. Notify your doctor immediately if you experience any of the following symptoms: fever, breathing trouble, weight gain, dizziness, chest pain, or unusual fatigue. It may be necessary for your doctor to use other medicines with tretinoin to reduce the chance of side effects. Vesanoid can cause severe birth defects when taken during pregnancy. Therefore, women who are pregnant must be informed of the risk to the fetus from tretinoin use. Women must avoid becoming pregnant while taking Vesanoid. Pregnancy tests should be performed 1 week before starting use of Vesanoid. Women should use 2 forms of contraception (birth control) at the same time, or avoid sexual intercourse, while taking Vesanoid and for 1 month after tretinoin use has been stopped. Women must also have monthly pregnancy testing and birth control counseling from their doctor while taking Vesanoid.

Vesanoid is used for:

Initiating remission for a certain type of acute promyelocytic leukemia (APL) that has failed to respond to other therapies. It may also be used for other conditions as determined by your doctor.

Vesanoid is a retinoid. How it works in APL is not completely understood. It is thought to decrease the growth of cells associated with APL.

Do NOT use Vesanoid if:

• you are allergic to any ingredient in Vesanoid, including the preservative parabens

Contact your doctor or health care provider right away if any of these apply to you.

Before using Vesanoid:

Some medical conditions may interact with Vesanoid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have an abnormally high white blood cell count

Some MEDICINES MAY INTERACT with Vesanoid. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Aminocaproic acid, aprotinin, imidazoles (eg, ketoconazole), tetracyclines (eg, doxycycline), tranexamic acid, or vitamin A because the risk of serious side effects may be increased


• Progesterone-only birth control pills because their effectiveness may be decreased by Vesanoid

This may not be a complete list of all interactions that may occur. Ask your health care provider if Vesanoid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Vesanoid:

Use Vesanoid as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Vesanoid by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.


• If you miss a dose of Vesanoid, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Vesanoid.

Important safety information:

• Vesanoid may cause dizziness or severe headache. These effects may be worse if you take it with alcohol or certain medicines. Use Vesanoid with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• If headache, nausea, vision changes, or vomiting occur, contact your doctor immediately. These could be the signs of increased pressure in the brain, a serious side effect.


• Lab tests, including pregnancy tests, blood clotting factors, blood cholesterol and triglyceride levels, liver function, and white blood cell counts, may be performed while you use Vesanoid. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Vesanoid should not be used in CHILDREN younger than 1 year old; safety and effectiveness in these children have not been confirmed.


• Caution is advised when using Vesanoid in CHILDREN; they may be more sensitive to its effects, especially increased pressure in the brain.


• Women taking Vesanoid should use 2 methods of birth control during and for 1 month after using Vesanoid.


• Progesterone-only birth control pills may not work as well while you are taking Vesanoid. Talk to your doctor about effective forms of birth control.


• PREGNANCY and BREAST-FEEDING: Do not use Vesanoid if you are pregnant. It has been shown to cause harm to the fetus. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. It is not known if Vesanoid is found in breast milk. Do not breast-feed while taking Vesanoid.

Possible side effects of Vesanoid:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Bone pain; dry skin and mouth; fever; hair loss; headache; increased sweating; itching; nausea; rash; tiredness; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); dizziness; hearing loss; heart attack; severe headache; shortness of breath; unusual bruising or bleeding; vision changes; weight gain.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Vesanoid side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include clumsiness; dizziness; flushing; headache; stomach pain.

Proper storage of Vesanoid:

Store Vesanoid at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Vesanoid out of the reach of children and away from pets.

General information:

• If you have any questions about Vesanoid, please talk with your doctor, pharmacist, or other health care provider.


• Vesanoid is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Vesanoid. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Vesanoid resources

• Vesanoid Side Effects (in more detail)
• Vesanoid Use in Pregnancy & Breastfeeding
• Drug Images
• Vesanoid Drug Interactions
• Vesanoid Support Group
• 1 Review for Vesanoid - Add your own review/rating

• Vesanoid Prescribing Information (FDA)


• Vesanoid Advanced Consumer (Micromedex) - Includes Dosage Information


• Vesanoid Concise Consumer Information (Cerner Multum)


• Vesanoid Monograph (AHFS DI)


• Tretinoin Prescribing Information (FDA)

Compare Vesanoid with other medications

• Acute Promyelocytic Leukemia

Ventolin Aerosol

Pronunciation: al-BUE-ter-ol
Generic Name: Albuterol
Brand Name: Examples include Proventil and Ventolin

Ventolin Aerosol is used for:

Treating or preventing breathing problems in patients who have asthma or certain other airway diseases. It may be used to prevent breathing problems caused by exercise. It may also be used for other conditions as determined by your doctor.

Ventolin Aerosol is a sympathomimetic (beta agonist) bronchodilator. It works by relaxing the smooth muscle in the airway, which allows air to flow in and out of the lungs more easily.

Do NOT use Ventolin Aerosol if:

• you are allergic to any ingredient in Ventolin Aerosol


• you are using another short-acting sympathomimetic bronchodilator (eg, metaproterenol)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Ventolin Aerosol:

Some medical conditions may interact with Ventolin Aerosol. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a history of heart problems, (eg, fast or irregular heartbeat, low blood output), blood vessel problems, high blood pressure, or low blood potassium levels


• if you have a history of seizures, diabetes, an overactive thyroid, kidney problems, or an adrenal gland tumor (pheochromocytoma)


• if you have ever had an unusual reaction to another sympathomimetic medicine (eg, pseudoephedrine)


• if you are taking a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) or tricyclic antidepressant (eg, amitriptyline), or if you have taken either of these medicines within the last 14 days

Some MEDICINES MAY INTERACT with Ventolin Aerosol. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Diuretics (eg, furosemide, hydrochlorothiazide) because the risk of low blood potassium levels may be increased


• Catechol-O-methyltransferase (COMT) inhibitors (eg, entacapone), MAOIs (eg, phenelzine), short-acting sympathomimetic bronchodilators (eg, metaproterenol), stimulants (eg, amphetamine), sympathomimetics (eg, pseudoephedrine), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Ventolin Aerosol's side effects


• Beta-blockers (eg, propranolol) because they may decrease Ventolin Aerosol's effectiveness


• Digoxin because its effectiveness may be decreased by Ventolin Aerosol

This may not be a complete list of all interactions that may occur. Ask your health care provider if Ventolin Aerosol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Ventolin Aerosol:

Use Ventolin Aerosol as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with Ventolin Aerosol. Talk to your pharmacist if you have questions about this information.


• Ventolin Aerosol is for oral inhalation only. Do not spray in the eyes. If you get Ventolin Aerosol in the eyes, rinse immediately with cool tap water.


• Prime the inhaler before the first use, any time it has not been used for more than 2 weeks, or if it has been dropped. To prime the inhaler, point it away from you and others. Spray 4 times, shaking well before each spray. If the inhaler has not been used for at least 4 days, re-prime by spraying 2 times.


• Before using Ventolin Aerosol, be sure that the canister is properly placed in the inhaler unit. Shake well before each use. Remove the protective cap from the mouthpiece and check to make sure there are no hidden foreign objects. Breathe out slowly and completely. Place the mouthpiece between your lips and try to rest your tongue flat, unless your doctor has told you otherwise. Your doctor may have told you to hold the inhaler 1 or 2 inches (2 or 3 centimeters) away from the open mouth or to use a special spacing device. As you start to take a slow deep breath, press the canister and mouthpiece together at exactly the same time. This will release a dose of Ventolin Aerosol. Continue breathing in slowly and deeply and hold for as long as comfortable (up to 10 seconds), then breathe out slowly through pursed lips or your nose. If more than 1 inhalation is to be used, wait 1 minute and repeat the above steps. Keep the spray away from your eyes.


• Ventolin Aerosol may cause dry mouth or an unpleasant taste in your mouth. Rinsing your mouth with water after each dose may help relieve these effects.


• Clean the plastic mouthpiece and cap at least once a week to prevent blockage. Remove the metal canister. Rinse in warm running water for 30 seconds. Shake off excess water, and then allow the mouthpiece to air dry completely (eg, overnight). After the plastic case and cap dry, replace the canister. Spray 1 time into the air away from yourself and others. Place the cap back on the mouthpiece. Do NOT allow the metal canister to become wet.


• If you must use the inhaler before it is completely dry, shake the excess water off of the plastic mouthpiece. Shake the canister well, then insert into the plastic case and spray 1 time into the air away from yourself and others. You may then use a dose. After your dose, rewash the plastic case and air dry completely.


• If the inhaler becomes blocked, wash the plastic case as directed.


• This inhaler contains 200 sprays. Do not use this inhaler after 200 sprays have been used. It may not give the correct amount of medicine with each spray.


• Do not use Ventolin Aerosol with any other mouthpiece. Do not use this mouthpiece with any other medicine.


• Do not stop using Ventolin Aerosol without checking with your doctor.


• If you miss a dose of Ventolin Aerosol and you are using it regularly, use it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Ventolin Aerosol.

Important safety information:

• Ventolin Aerosol may cause dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Ventolin Aerosol with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Ventolin Aerosol may sometimes cause severe breathing problems right after you use a dose. When this problem occurs, it is often after the first use of a new canister or vial. If this happens, seek medical care at once.


• If your usual dose does not work well, your symptoms become worse, or you need to use it more often than normal, contact your doctor at once. This may be a sign of seriously worsening asthma. Your doctor may need to change your dose or medicine.


• Ventolin Aerosol should work for up to 6 hours. Do NOT use more than the recommended dose or use more often than prescribed without checking with your doctor. The risk of severe heart problems and sometimes death may be increased with overuse of Ventolin Aerosol.


• Some patients may have trouble using Ventolin Aerosol correctly. Some may also get mouth sores or a bad taste in the mouth after using it. If you have any of these problems, ask your health care provider if a spacing device may help.


• Tell your doctor or dentist that you take Ventolin Aerosol before you receive any medical or dental care, emergency care, or surgery.


• Talk with your doctor or pharmacist about all of your asthma medicines and how to use them. Do not start, stop, or change the dose of any asthma medicine unless your doctor tells you to.


• Keep track of how many inhalations you use. When your medicine supply begins to run low, call your doctor or pharmacy as soon as possible for a refill.


• Do NOT place the canister in water to try to determine how much medicine you have left.


• The contents of this canister are under pressure. Do NOT puncture, break, or burn container, even if it appears empty.


• Diabetes patients - Ventolin Aerosol may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.


• Use Ventolin Aerosol with caution in the ELDERLY; they may be more sensitive to its effects.


• Caution is advised when using Ventolin Aerosol in CHILDREN; they may be more sensitive to its effects.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Ventolin Aerosol while you are pregnant. It is not known if Ventolin Aerosol is found in breast milk. If you are or will be breast-feeding while you use Ventolin Aerosol, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Ventolin Aerosol:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Cough; headache; nausea; nervousness; sinus inflammation; sore or dry throat; tremor; trouble sleeping; unusual taste in mouth; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; fast or irregular heartbeat; new or worsened trouble breathing; pounding in the chest; severe headache or dizziness; unusual hoarseness; wheezing.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Ventolin side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include chest pain; fast or irregular heartbeat; seizures; severe headache or dizziness; severe or persistent nervousness or trouble sleeping; tremor.

Proper storage of Ventolin Aerosol:

Store Ventolin Aerosol upright between 59 and 77 degrees F (15 and 25 degrees C). Do not freeze. Contents are under pressure. Do not puncture. Do not use or store near heat or open flame. Do not expose the container to temperatures above 120 degrees F (48 degrees C). The container may burst. Store the inhaler with the mouthpiece down. Do not use after the expiration date on the container or box. Keep Ventolin Aerosol out of the reach of children and away from pets.

General information:

• If you have any questions about Ventolin Aerosol, please talk with your doctor, pharmacist, or other health care provider.


• Ventolin Aerosol is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Ventolin Aerosol. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Ventolin resources

• Ventolin Side Effects (in more detail)
• Ventolin Use in Pregnancy & Breastfeeding
• Drug Images
• Ventolin Drug Interactions
• Ventolin Support Group
• 6 Reviews for Ventolin - Add your own review/rating

Compare Ventolin with other medications

• Asthma, acute
• Asthma, Maintenance
• Bronchospasm Prophylaxis
• COPD, Acute
• COPD, Maintenance

Vetscription Benadene

Dosage Form: FOR ANIMAL USE ONLY
Sergeant's Vetscription Benadene For Puppies and Dogs

INDICATIONS & USAGE:

No sting formula


Signs of hot spots include

• reddened areas
  


• hair loss


• intense itching
  

Sergeant's Vetscription Benadene hot spot skin remedy for dogs and puppies is formulated to be effective for skin irritations.  Specifically kills staphylococcus intermedius bacteria.  Hot spots in dogs are commonly associated with staphylococcus intermedius.  Kills topical bacteria, fungus and viruses.  Benadene is indicated for superficial cuts, scrapes, and abrasions.  Best of all, Benadene contains no alcohol and is a non-stinging formula.


Signs of Hot Spots:  Hot spots are usually accompanied by incessant rubbing, scratching, and biting due to intense itching.  Other signs are moist reddened areas, hair loss, and flaky skins.  Hot spots are usually warm to the touch.

GENERAL PRECAUTIONS:

FOR ANIMAL USE ONLY


Consult veterinarian if any problems persist or are of concern.

DIRECTIONS FOR USE:

Trim the hair around the sore.  Wash the area with mild soap and water, rinse, and pat dry.  Apply Benadene to affected area using the applicator tip.  Does not require dabbing on with a cotton ball.  Do not use on puppies under 6 weeks of age.

KEEP OUT OF REACH OF CHILDREN

QUESTIONS/COMMENTS

Sergeant's is committed to providing high quality products.  If you have questions or comments about the product, please write:  Sergeant's consumer Response, PO Box 54099, Omaha, NE 68154-0399.


In case of an Emergency call:  1-800-781-4738.

Non-Emergency call:  1-800-224-PETS(7387).

RECOMMENDED STORAGE:

STORE BELOW 30 DEGREES C (86 DEGREES F)

PACKAGE LABEL PRINCIPAL DISPLAY PANEL

Vetscription Benadene For Puppies and Dogs


Distributed by:


Sergant's Pet Care Products, Inc, Omaha, NE 68130


MADE IN USA


www.sergeants.com

Vetscription Benadene  benzalkonium chloride  gel

Product Information Product Type OTC ANIMAL DRUG NDC Product Code (Source) 21091-122 Route of Administration TRANSDERMAL DEA Schedule

Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength Benzalkonium Chloride (BENZALKONIUM) Benzalkonium Chloride 0.16284 mL  in 118 mL

Inactive Ingredients Ingredient Name Strength No Inactive Ingredients Found

Product Characteristics Color blue (blue/green) Score      Shape Size Flavor Imprint Code Contains

Packaging # NDC Package Description Multilevel Packaging 1 21091-122-04 118 mL In 1 BOTTLE, PLASTIC None

Marketing Information
Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
unapproved drug other		09/21/2005

Labeler - Sergeant's Pet Care Products, Inc. (876995171)

Establishment
Name	Address	ID/FEI	Operations
Straight Arrow Products, Inc.		061580593	manufacture

Revised: 09/2010Sergeant's Pet Care Products, Inc.

verteporfin Intravenous, Injection

ver-te-PORE-fin

Commonly used brand name(s)

In the U.S.

• Visudyne

Available Dosage Forms:

• Powder for Solution

Therapeutic Class: Photosensitizing Agent

Uses For verteporfin

Verteporfin is used together with a special laser light, to treat abnormal blood vessel formation in a part of the eye which, if left untreated, can lead to a loss of eyesight.

Verteporfin may also be used for the following problems:

• Pathologic myopia (changes in the eyeball causing vision problems);


• Ocular histoplasmosis (damage to the eye from a fungus found in the soil)

verteporfin is to be administered only by or under the immediate supervision of your doctor.

Before Using verteporfin

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For verteporfin, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to verteporfin or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies on verteporfin have been done only in adult patients, and there is no specific information comparing use of verteporfin in children with use in other age groups.

Geriatric

Studies show that the effects of verteporfin are less in patients 75 years of age or older.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of verteporfin. Make sure you tell your doctor if you have any other medical problems, especially:

• Liver function impairment


• Porphyria—Sensitivity to light may be increased


• Previous reaction to verteporfin—Reaction is more likely to occur again

Proper Use of verteporfin

Treatment with verteporfin and laser light occurs in two steps. First, the verteporfin is injected into your body. Second, 15 minutes later, a laser light is directed at the affected eye.

Dosing

The dose of verteporfin will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of verteporfin. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

Precautions While Using verteporfin

For 5 days after you receive an injection of verteporfin, your eyes will be extra sensitive to light, including sunlight and bright indoor lights. Certain types of sunglasses can help protect your eyes during this time. Check with your doctor about which sunglasses to use.

For 5 days after you receive an injection of verteporfin, your skin will be extra sensitive to sunlight and to very bright indoor lights, such as tanning lamps, bright halogen lighting and lights in dental offices or operating rooms. Do not expose your skin to direct sunlight or to bright indoor lights during this time. Sunscreens will not protect your skin from a severe reaction to light (blistering, burning, and swelling of the skin). However, exposure to normal amounts of indoor light (for example, daylight or light from lamps with shades) will help clear up the verteporfin remaining in your skin. Therefore, do not protect your skin from normal amounts of indoor light. If you have any questions about whether the light in your home is too bright, check with your doctor or nurse. If you do have a severe reaction to light, call your doctor immediately.

verteporfin Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Blurred vision or other change in vision

Less common

• Decrease in vision, may be severe


• dizziness


• dull nervousness


• eye pain


• fainting


• fast, slow, or irregular heartbeat


• itching, redness, or other irritation of eye


• pale skin


• pounding in the ears


• troubled breathing on exertion


• unusual bleeding or bruising


• unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, infection, itching, numbness, pain, rash, redness, scarring, stinging, swelling, tenderness, tingling, ulceration, and/or warmth at the injection site


• headache

Less common

• Back pain (during infusion of verteporfin)


• chills


• cloudy urine


• constipation


• cough


• decreased hearing


• decreased sensitivity to touch


• diarrhea


• difficult or painful urination


• difficulty in moving


• double vision


• dry eyes


• feeling of constant movement of self or surroundings


• fever


• general feeling of discomfort or illness


• hoarseness


• increased sensitivity of skin to sunlight


• joint pain


• light headedness


• loss of appetite


• loss of strength or energy


• muscle pain or stiffness


• nausea


• pain, swelling, or redness in joints


• pelvic discomfort


• redness or other discoloration of skin


• runny nose


• severe sunburn


• shivering


• skin rash


• sore throat


• sweating


• tearing


• tender, swollen glands in neck


• throat congestion


• trouble in sleeping


• trouble in swallowing


• trouble sleeping


• varicose veins


• voice changes


• vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: verteporfin Intravenous, Injection side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More verteporfin Intravenous, Injection resources

• Verteporfin Intravenous, Injection Side Effects (in more detail)
• Verteporfin Intravenous, Injection Use in Pregnancy & Breastfeeding
• Verteporfin Intravenous, Injection Drug Interactions
• Verteporfin Intravenous, Injection Support Group
• 0 Reviews for Verteporfin Intravenous, Injection - Add your own review/rating

Compare verteporfin Intravenous, Injection with other medications

• Macular Degeneration

VESIcare

Pronunciation: SOE-li-FEN-a-sin
Generic Name: Solifenacin
Brand Name: VESIcare

VESIcare is used for:

Treating overactive bladder with symptoms of an urgent need to urinate, a need to urinate often, or leakage of urine.

VESIcare is a muscarinic receptor antagonist. It works by blocking the action of certain chemicals in the body to help decrease urination problems caused by overactive bladder.

Do NOT use VESIcare if:

• you are allergic to any ingredient in VESIcare


• you have uncontrolled narrow-angle glaucoma


• you have severe liver problems


• you are unable to empty your bladder (urinary retention) or have slow or delayed emptying of your stomach (gastric retention)

Contact your doctor or health care provider right away if any of these apply to you.

Before using VESIcare:

Some medical conditions may interact with VESIcare. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have stomach or intestinal problems, constipation, difficulty urinating, or a weak urine stream


• if you have narrow-angle glaucoma, liver or kidney problems, or a history of heart problems (eg, QT prolongation)

Some MEDICINES MAY INTERACT with VESIcare. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Certain antifungal medicines (eg, itraconazole, ketoconazole), certain medicines for HIV infection (eg, ritonavir, saquinavir), macrolide antibiotics (eg, clarithromycin, erythromycin), or nefazodone because side effects, such as constipation or dry mouth, may occur


• Medicines that may affect your heart rate because side effects, including heart-related effects, may occur. If you are unsure if any of your medicines may affect your heart rate, ask your doctor or pharmacist

This may not be a complete list of all interactions that may occur. Ask your health care provider if VESIcare may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use VESIcare:

Use VESIcare as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with VESIcare. Talk to your pharmacist if you have questions about this information.


• Take VESIcare by mouth with or without food.


• Swallow VESIcare whole with liquids. Do not break, crush, or chew before swallowing.


• If you miss a dose of VESIcare, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use VESIcare.

Important safety information:

• VESIcare may cause dizziness or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use VESIcare with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Contact your doctor at once if you experience severe stomach pain or if you are constipated for 3 or more days.


• Heat exhaustion or heat stroke due to decreased sweating can occur while you are taking VESIcare (eg, if you become overheated in a warm environment or during increased physical activity). Seek immediate medical attention if you experience sudden or severe tiredness, weakness, anxiety, dizziness, or fainting.


• Use VESIcare with caution in the ELDERLY; they may be more sensitive to its effects.


• VESIcare should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you are pregnant or planning on becoming pregnant, contact your doctor. You will need to discuss the benefits and risks of using VESIcare while you are pregnant. It is not known if VESIcare is found in breast milk. Do not breast-feed while taking VESIcare.

Possible side effects of VESIcare:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; constipation; cough; dizziness; dry eyes; dry mouth; indigestion or stomach upset; tiredness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); back pain; bloody or cloudy urine; constipation lasting 3 or more days; fast, slow, or irregular heartbeat; fever or chills; mood or mental changes (eg, confusion, depression, hallucinations); pain below the ribs; pain while urinating; severe stomach pain; unusual or severe headache; urinary retention (unable to empty the bladder).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: VESIcare side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; tremors; unusually dry skin.

Proper storage of VESIcare:

Store VESIcare at 77 degrees F (25 degrees C). Brief storage in temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Keep VESIcare out of the reach of children and away from pets.

General information:

• If you have any questions about VESIcare, please talk with your doctor, pharmacist, or other health care provider.


• VESIcare is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about VESIcare. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More VESIcare resources

• VESIcare Side Effects (in more detail)
• VESIcare Use in Pregnancy & Breastfeeding
• Drug Images
• VESIcare Drug Interactions
• VESIcare Support Group
• 31 Reviews for VESIcare - Add your own review/rating

• VESIcare Prescribing Information (FDA)


• Vesicare Monograph (AHFS DI)


• Vesicare Advanced Consumer (Micromedex) - Includes Dosage Information


• Vesicare Consumer Overview

Compare VESIcare with other medications

• Overactive Bladder
• Urinary Incontinence

Ventolin Rotacaps

Generic Name: albuterol (Inhalation route)

al-BUE-ter-ol

Commonly used brand name(s)

In the U.S.

• Accuneb


• ProAir HFA


• Proventil


• Proventil HFA


• ReliOn Ventolin HFA


• Ventolin


• Ventolin HFA

In Canada

• Alti-Salbutamol Inhalation Aerosol


• Apo-Salvent


• Salbutamol


• Salbutamol Nebuamp


• Salbutamol Respirator Solution


• Ventolin Inhaler


• Ventolin Nebules P.F.


• Ventolin Respirator


• Ventolin Rotacaps

Available Dosage Forms:

• Aerosol Powder


• Solution


• Capsule


• Powder

Therapeutic Class: Bronchodilator

Pharmacologic Class: Sympathomimetic

Uses For Ventolin Rotacaps

Albuterol is used to treat or prevent bronchospasm in patients with asthma, bronchitis, emphysema, and other lung diseases. This medicine is also used to prevent wheezing caused by exercise (exercise-induced bronchospasm).

Albuterol belongs to the family of medicines known as adrenergic bronchodilators. Adrenergic bronchodilators are medicines that are breathed in through the mouth to open up the bronchial tubes (air passages) in the lungs. They relieve cough, wheezing, shortness of breath, and troubled breathing by increasing the flow of air through the bronchial tubes.

This medicine is available only with your doctor's prescription.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, albuterol is used in certain patients with the following medical condition:

• Hyperkalemia (too much potassium in the blood).

Before Using Ventolin Rotacaps

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of albuterol inhalation aerosol (e.g., Proair® HFA) in children 4 years of age and older and albuterol inhalation solution (e.g., Accuneb®) in children 2 years of age and older. However, safety and efficacy have not been established for the aerosol in children younger than 4 years of age and for the solution in children younger than 2 years of age.

Geriatric

No information is available on the relationship of age to the effects of albuterol inhalation solution (e.g., Accuneb®) in geriatric patients.

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of albuterol inhalation aerosol (e.g., Proair® HFA) in geriatric patients. However, elderly patients are more likely to have age-related heart or kidney problems, which may require caution and an adjustment in the dose for patients receiving albuterol.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Acebutolol


• Alprenolol


• Arotinolol


• Atenolol


• Atomoxetine


• Befunolol


• Betaxolol


• Bevantolol


• Bisoprolol


• Bopindolol


• Brofaromine


• Bucindolol


• Bupranolol


• Carteolol


• Carvedilol


• Celiprolol


• Clorgyline


• Dilevalol


• Esmolol


• Furazolidone


• Iproniazid


• Isocarboxazid


• Labetalol


• Landiolol


• Lazabemide


• Levobetaxolol


• Levobunolol


• Linezolid


• Mepindolol


• Metipranolol


• Metoprolol


• Moclobemide


• Nadolol


• Nebivolol


• Nialamide


• Nipradilol


• Oxprenolol


• Pargyline


• Penbutolol


• Phenelzine


• Pindolol


• Procarbazine


• Propranolol


• Rasagiline


• Selegiline


• Sotalol


• Talinolol


• Tertatolol


• Timolol


• Toloxatone


• Tranylcypromine

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Diabetes or


• Heart or blood vessel disease or


• Heart rhythm problems (e.g., arrhythmia) or


• Hypertension (high blood pressure) or


• Hyperthyroidism (overactive thyroid) or


• Hypokalemia (low potassium in the blood) or


• Seizures, history of—Use with caution. May make these conditions worse.

• Kidney disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

Proper Use of albuterol

This section provides information on the proper use of a number of products that contain albuterol. It may not be specific to Ventolin Rotacaps. Please read with care.

Use this medicine only as directed by your doctor. Do not use more of it and do not use it more often than your doctor ordered. Also, do not stop using this medicine or any asthma medicine without telling your doctor. To do so may increase the chance for breathing problems.

The albuterol inhalation solution (e.g., Accuneb®) should be used with a jet nebulizer that is connected to an air compressor with good air flow. The inhalation solution and nebulizer will come with patient instructions. Read and follow these instructions carefully. Ask your doctor if you have any questions.

To use the inhalation solution in the nebulizer:

• Use one container of solution or mix the exact amount of solution using the dropper provided for each dose.


• Place the inhalation solution in the medicine reservoir or nebulizer cup on the machine.


• Connect the nebulizer to the face mask or mouthpiece.


• Use the face mask or mouthpiece to breathe in the medicine.


• Use the nebulizer for about 5 to 15 minutes, or until the medicine in the nebulizer cup is gone.


• Clean all the parts of the nebulizer after each use.

The albuterol inhalation aerosol (e.g., Proair® HFA) is used with a special inhaler that comes with patient instructions. Read the directions carefully before using this medicine. If you or your child do not understand the directions or are not sure how to use the inhaler, ask your doctor to show you what to do. Also, ask your doctor to check you or your child on a regular basis to make sure you are using it properly.

To use the aerosol inhaler:

• The inhaler should be at room temperature before you use it.


• Insert the metal canister firmly and fully into the clear end of the Proair® HFA mouthpiece. This mouthpiece should not be used with other inhaled medicines.


• Remove the cap and look at the mouthpiece to make sure it is clean.


• Shake the inhaler well and test spray it in the air 3 times before using it for the first time or if the inhaler has not been used for more than 2 weeks.


• To inhale this medicine, breathe out fully, trying to get as much air out of the lungs as possible. Put the mouthpiece just in front of your mouth with the canister upright.


• Open your mouth and breathe in slowly and deeply (like yawning), and at the same time firmly press down once on the top of the canister.


• Hold your breath for about 10 seconds, then breathe out slowly.


• If you are supposed to use more than one puff, wait 1 minute before inhaling the second puff. Repeat these steps for the second puff, starting with shaking the inhaler.


• When you have finished all of your doses, rinse your mouth with water and spit the water out.


• Clean the inhaler mouthpiece at least once a week with warm running water for 30 seconds, and dry it completely.


• If you need to use the inhaler before it is completely dry, shake off the excess water, replace the canister, and spray it 2 times in the air away from the face. Use your regular dose.


• After using the inhaler, wash the mouthpiece again and dry it completely.


• If the mouthpiece becomes blocked, washing it will help.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For inhalation aerosol dosage form (inhaler):
  
  • For preventing bronchospasm:
    
    • Adults, teenagers, and children 4 years of age and older—Two puffs every 4 to 6 hours as needed.
    
    
    • Children younger than 4 years of age—Use and dose must be determined by your child's doctor.
    
    
  
  
  • For preventing exercise-induced bronchospasm:
    
    • Adults, teenagers, and children 4 years of age and older—Two puffs taken 15 to 30 minutes before exercise.
    
    
    • Children younger than 4 years of age—Use and dose must be determined by your child's doctor.
    
    
  
  


• For inhalation solution dosage form (used with a nebulizer):
  
  • For preventing bronchospasm:
    
    • Adults and children older than 12 years of age—2.5 milligrams (mg) in the nebulizer 3 or 4 times per day as needed.
    
    
    • Children 2 to 12 years of age—0.63 to 1.25 mg in the nebulizer 3 or 4 times per day as needed.
    
    
    • Children younger than 2 years of age—Use and dose must be determined by your child's doctor.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the canister at room temperature, away from heat and direct light. Do not freeze. Do not keep this medicine inside a car where it could be exposed to extreme heat or cold. Do not poke holes in the canister or throw it into a fire, even if the canister is empty.

Keep the medicine in the foil pouch until you are ready to use it. Store at room temperature, away from heat and direct light. Do not freeze.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using Ventolin Rotacaps

It is very important that your doctor check the progress of you or your child at regular visits. This will allow your doctor to see if the medicine is working properly and to check for any unwanted effects.

This medicine should not be used together with other inhaled medicines that are similar, such as isoproterenol (Isuprel®), levalbuterol (Xopenex™), metaproterenol (Alupent®), pirbuterol (Maxair®), or terbutaline (Brethaire®).

This medicine may cause paradoxical bronchospasm, which means your breathing or wheezing will get worse. Paradoxical bronchospasm may be life-threatening. Stop using this medicine and check with your doctor right away if you or your child have coughing, difficulty breathing, shortness of breath, or wheezing after using this medicine.

Talk to your doctor or get medical help right away if:

• Your symptoms do not improve or they become worse after using this medicine.


• Your inhaler does not seem to be working as well as usual and you need to use it more often.

You or your child may also be taking an antiinflammatory medicine, such as a steroid (cortisone-like medicine), together with this medicine. Do not stop taking the antiinflammatory medicine, even if your asthma seems better, unless you are told to do so by your doctor.

Albuterol may cause serious types of allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Stop using this medicine and check with your doctor right away if you or your child develop a skin rash, hives, itching, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth while you are using this medicine.

Hypokalemia (low potassium in the blood) may occur while you are using this medicine. Check with your doctor right away if you or your child have more than one of the following symptoms: convulsions; decreased urine; dry mouth; increased thirst; irregular heartbeat; loss of appetite; mood changes; muscle pain or cramps; nausea or vomiting; numbness or tingling in the hands, feet, or lips; shortness of breath; or unusual tiredness or weakness.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines for appetite control, asthma, colds, cough, hay fever, or sinus problems, and herbal or vitamin supplements.

Ventolin Rotacaps Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Fast, irregular, pounding, or racing heartbeat or pulse


• shakiness in the legs, arms, hands, or feet


• trembling or shaking of the hands or feet

Less common

• Abdominal or stomach pain


• bladder pain


• bloody or cloudy urine


• chest discomfort


• chest pain


• cough or hoarseness


• cough producing mucus


• diarrhea


• difficult or labored breathing


• difficulty with swallowing


• dizziness


• feeling of warmth


• fever or chills


• frequent urge to urinate


• hives


• itching


• loss of appetite


• lower back or side pain


• nausea


• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue


• redness of the face, neck, arms, and occasionally, upper chest


• runny nose


• shortness of breath


• skin rash


• sore throat


• swollen, painful, or tender lymph glands in the neck, armpit, or groin


• tightness in the chest


• unusual tiredness or weakness


• weakness


• wheezing

Rare

• Hives or welts


• large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs


• noisy breathing


• redness of the skin


• swelling of the mouth or throat


• trouble breathing

Incidence not known

• Agitation


• anxiety


• arm, back, or jaw pain


• chest tightness or heaviness


• confusion


• convulsions


• decreased urine


• dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position


• drowsiness


• dry mouth


• extra heartbeats


• fainting


• flushed, dry skin


• fruit-like breath odor


• hallucinations


• headache


• increased hunger


• increased thirst


• increased urination


• irritability


• lightheadedness


• muscle pain or cramps


• nervousness


• nightmares


• numbness or tingling in the hands, feet, or lips


• pounding in the ears


• rapid, deep breathing


• restlessness


• shakiness


• slow or fast heartbeat


• stomach cramps


• sweating


• unexplained weight loss


• unusual feeling of excitement


• vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Body aches or pain


• congestion


• fever


• runny nose


• tender, swollen glands in the neck


• trouble with swallowing


• voice changes

Less common

• Difficult, burning, or painful urination


• earache


• headache, severe and throbbing


• muscle or bone pain


• pain


• redness of the skin


• redness or swelling in the ear


• redness, swelling, or soreness of the tongue


• sleeplessness


• sneezing


• stuffy nose


• swelling


• tenderness


• trouble in holding or releasing urine


• trouble sleeping


• unable to sleep


• warmth on the skin

Rare

• Sleepiness or unusual drowsiness

Incidence not known

• Bad, unusual, or unpleasant (after) taste


• change in taste


• feeling of constant movement of self or surroundings


• gagging


• rough, scratchy sound to voice


• sensation of spinning


• tightness in the throat

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Ventolin Rotacaps side effects (in more detail)

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• Ventolin Rotacaps Side Effects (in more detail)
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• Drug Images
• Ventolin Rotacaps Drug Interactions
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